GLP-2 TR research: overview and resources
What GLP-2 TR research material is, how it is characterized, and where to find every specification, method, lot record and reference GLP2 Labs publishes about it.
What is GLP-2 TR?
GLP-2 TR is a synthetic 39-residue research peptide designed as an agonist at two class B G protein-coupled receptors: the GIP receptor (GIPR) and the GLP-1 receptor (GLP-1R). Its backbone contains two α-aminoisobutyric acid (Aib) residues, at positions 2 and 13, which constrain the chain and protect it from dipeptidyl peptidase-4, and lysine 20 carries a C20 fatty diacid attached through a γ-glutamate and two AEEA spacers. The C-terminal nine residues end in an amidated serine.
GLP2 Labs supplies GLP-2 TR as a lyophilized powder in 30 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity against a reference standard and net content, with a fentanyl screen, and the result is published here before sale through Klow.bio.
"GLP-2 TR" is a product name for this two-receptor design. It is not glucagon-like peptide-2 (GLP-2), the natural 33-residue peptide cut from proglucagon, and it is not designed for the GLP-2 receptor. That is why GLP2 Labs identifies the material by its sequence, formula and lot results rather than by name alone.
What is GLP-2 TR research material?
GLP-2 TR research material is GLP-2 TR supplied for laboratory research (C225H348N48O68, 4813.45 g/mol) in lyophilized powder form, sold by lot. Each lot's identity, purity and net content are documented by an independent laboratory in a published certificate of analysis.
How is GLP-2 TR characterized?
Three questions are answered for every lot, each by a different method:
- Is it the right compound? The laboratory runs the sample and a reference standard of the named compound under the same HPLC conditions; identity is confirmed when the main peak elutes at the reference standard’s retention time.
- How much of the sample is that compound? HPLC-UV reports the main peak's share of detected peak area. Current lots: 99.77%.
- How much peptide is in the vial? Net content is measured directly.
Endotoxin (LAL) and microbial DNA (PCR) results are added where those tests are run.
What has not been established
A certificate of analysis describes the specific sample tested on its test date. It does not establish stability afterward, sequence order beyond what mass confirmation shows, results for other lots, or suitability for any particular purpose.
GLP-2 TR at a glance
- Product
- GLP-2 TR
- Type
- Synthetic dual-receptor research peptide (39 residues), 39 residues
- Receptor design
- GIP receptor (GIPR) and GLP-1 receptor (GLP-1R)
- Molecular formula
- C225H348N48O68
- Molecular weight
- 4813.45 g/mol (average)
- Form
- Lyophilized powder
- Vial sizes
- 30 mg
- Purity, current lots
- 99.77% (HPLC-UV)
- Purity specification
- ≥95%
- Identity
- Confirmed by HPLC retention-time match on every lot
- Testing laboratory
- ILS Laboratories (independent)
- Current lot
- KB-52383, reported Sep 23, 2026
- Operated by
- Klow Labs LLC, Chicago, IL
- Where to order
- klow.bio
GLP-2 TR research resources
Every GLP-2 TR resource on glp2.bio, organized from chemistry to documentation.
GLP-2 TR specifications
Formula, molecular weight, sequence, modifications and release specification.
QualityQuality and supply chain
Sourcing, specifications, batch documentation and release.
TestingAnalytical testing
How every lot is tested, reviewed and released.
TestingHPLC analysis of GLP-2 TR
Retention time, peaks, area normalization and results by lot.
DocumentationCertificates of analysis
Every lot's full results, plus the complete testing records.
DocumentationHow to read a GLP-2 TR COA
What each section means and what a COA does and doesn't establish.
DocumentationVerify a lot
Look up any GLP-2 TR lot by the number on the vial.
AnalysisPurity, content and net content
Three different numbers, kept apart.
HandlingStorage and stability
Degradation pathways and lyophilized peptide handling.
ReferenceGlossary
Definitions for every term on a GLP-2 TR certificate.
Research materialGLP-2 TR research material
Sizes, current lots and availability. Purchasing is handled through Klow.bio.
Research references
Published sources
- NCBI Gene: GIPR (gastric inhibitory polypeptide receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/2696
- NCBI Gene: GLP1R (glucagon like peptide 1 receptor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/2740
- NCBI Gene: GCG (glucagon; proglucagon, the GLP-2 precursor). National Center for Biotechnology Information, NIH. www.ncbi.nlm.nih.gov/gene/2641
- PubChem: 2-Aminoisobutyric acid. National Library of Medicine, NIH. pubchem.ncbi.nlm.nih.gov/compound/2-Aminoisobutyric-acid
- Wilm M. Principles of electrospray ionization. Mol Cell Proteomics. 2011. PMC3134074. pmc.ncbi.nlm.nih.gov/articles/PMC3134074
- U.S. FDA. Q2(R2) Validation of Analytical Procedures. 2024. fda.gov
- U.S. FDA. Pyrogen and Endotoxins Testing: Questions and Answers. Revised 2026. fda.gov
GLP2 Labs analytical documentation
- Lot KB-52383: 30 mg, 99.77% purity, reported Sep 23, 2026
- GLP-2 TR testing records (all tests, all lots; CSV available)
Editorial scope
GLP2 Labs research content covers molecular characteristics, peptide structure, analytical chemistry, purity and identity testing, certificates of analysis, lot documentation and laboratory storage and handling.
It does not cover dosing, administration instructions, protocols, personal use or medical advice.
Latest updates
Buy GLP-2 TR
30 mg vials. Current lot KB-52383 tested at 99.77% purity with identity confirmed by HPLC retention-time match against a reference standard. Current purchasing is available through Klow.bio.